Unmasking the bias: Can diffusion-weighted imaging reliably assess glymphatic function in awake and anesthetized brain?

Ryszard Stefan Gomolka, Antonio Ladrón-de-Guevara, Sören Grubb, Lydiane Hirschler, Isabelle Strom, Pia Weikop, Matthias van Osch, Maiken Nedergaard, Yuki Mori

NeuroImage, vol. 328, 2026, p. 121761

MR-AIV reveals in vivo brain-wide fluid flow with physics-informed AI

Juan Diego Toscano, Yisen Guo, Zhibo Wang, Mohammad Vaezi, Yuki Mori, George Em Karniadakis, Kimberly AS Boster, Douglas H Kelley

Science Advances, vol. 12, 2026, pp. eaeb0404

Chronotherapy to reinforce circadian rhythms improves poststroke outcomes and glymphatic function in mice

Emma Waight, Yuxi Zhu, Ashley Caudell, Velia S Vizcarra, Evan Newbold, Michael J Giannetto, Evalien Duyvestyn, Estephanie Balbuena, Wei Song, Tanzil M Arefin, Yuki Mori, Maiken Nedergaard, Lauren M Hablitz

The Journal of Clinical Investigation, vol. 136, 2026, pp. e201800

Current Trends in Preclinical and Translational MRI in Neurofluids Research

Yuki Mori

InnerVision, vol. 40, 2025, pp. 13--18

A curious concept of CNS clearance

Virginia Plá, Erik Kroesbergen, Saiyue Deng, Michael J Giannetto, Lauren M Hablitz, Evan Newbold, Antonio Ladrón-de-Guevara, Tina Esmail, Ryszard S Gomolka, Yuki Mori, Douglas H Kelley, John H Thomas, Steven A Goldman, Maiken Nedergaard

Nature Neuroscience, vol. 28, 2025, pp. 731--733

Current Understanding of the Anatomy, Physiology, and Magnetic Resonance Imaging of Neurofluids: Update From the 2022 ISMRM Imaging Neurofluids Study group Workshop in Rome

Nivedita Agarwal, Laura D. Lewis, Lydiane Hirschler, Leonardo Rivera Rivera, Shinji Naganawa, Swati Rane Levendovszky, Geir Ringstad, Marijan Klarica, Joanna Wardlaw, Costantino Iadecola, Cheryl Hawkes, Roxana Octavia Carare, Jack Wells, Erik N.T.P. Bakker, Vartan Kurtcuoglu, Lynne Bilston, Maiken Nedergaard, Yuki Mori, Marcus Stoodley, Noam Alperin, Mony de Leon, Matthias J.P. van Osch

Journal of Magnetic Resonance Imaging, vol. 59, 2024, pp. 431--449

Modeling of brain efflux: Constraints of brain surfaces

Peter A. R. Bork, Natalie L. Hauglund, Yuki Mori, Kjeld Møllgård, Poul G. Hjorth, Maiken Nedergaard

Proceedings of the National Academy of Sciences, vol. 121, 2024, pp. e2318444121

Transient but not chronic hyperglycemia accelerates ocular glymphatic transport

Christine Delle, Xiaowei Wang, Michael Giannetto, Evan Newbold, Weiguo Peng, Ryszard Stefan Gomolka, Antonio Ladrón-de-Guevara, Neža Cankar, Elise Schiøler Nielsen, Celia Kjaerby, Pia Weikop, Yuki Mori, Maiken Nedergaard

Fluids and Barriers of the CNS, vol. 21, 2024, p. 26

Glymphatic fluid transport is suppressed by the aquaporin‐4 inhibitor AER‐271

Michael J. Giannetto, Ryszard S. Gomolka, Daniel Gahn‐Martinez, Evan J. Newbold, Peter A. R. Bork, Ethan Chang, Michael Gresser, Trevor Thompson, Yuki Mori, Maiken Nedergaard

Glia, vol. 72, 2024, pp. 982--998

Trigeminal ganglion neurons are directly activated by influx of CSF solutes in a migraine model

Martin Kaag Rasmussen, Kjeld Møllgård, Peter AR Bork, Pia Weikop, Tina Esmail, Lylia Drici, Nicolai J Wewer Albrechtsen, Jonathan Frederik Carlsen, Nguyen PT Huynh, Nima Ghitani, Matthias Mann, Steven A Goldman, Yuki Mori, Alexander T Chesler, Maiken Nedergaard

Science, vol. 385, 2024, pp. 80--86

Glymphatic clearance is enhanced during sleep

Erik Kroesbergen, Laurence Vince Riesselmann, Ryszard Stefan Gomolka, Virginia Pla, Tina Esmail, Visti Hildebrandt Stenmo, Eszter Rebeka Kovacs, Elise Schioler Nielsen, Steven Alan Goldman, Maiken Nedergaard, Pia Weikop, Yuki Mori

bioRxiv, 2024, pp. 2024--08

Emerging insights into cerebrospinal fluid dynamics and glial involvement therein

Yuki Mori, Hajime Hirase

Jpn J Cell, vol. 56, 2024, pp. 579--583

Long-term high-fat diet increases glymphatic activity in the hypothalamus in mice

Christine Delle, Neža Cankar, Christian Digebjerg Holgersson, Helle Hvorup Knudsen, Elise Schiøler Nielsen, Celia Kjaerby, Yuki Mori, Maiken Nedergaard, Pia Weikop

Scientific Reports, vol. 13, 2023, p. 4137

Loss of aquaporin-4 results in glymphatic system dysfunction via brain-wide interstitial fluid stagnation

Ryszard Stefan Gomolka, Lauren M Hablitz, Humberto Mestre, Michael Giannetto, Ting Du, Natalie Linea Hauglund, Lulu Xie, Weiguo Peng, Paula Melero Martinez, Maiken Nedergaard, Yuki Mori

eLife, vol. 12, 2023, p. 82232

Delivery of gene therapy through a cerebrospinal fluid conduit to rescue hearing in adult mice

Barbara K. Mathiesen, Leo M. Miyakoshi, Christopher R. Cederroth, Evangelia Tserga, Corstiaen Versteegh, Peter A.R. Bork, Natalie L. Hauglund, Ryszard Stefan Gomolka, Yuki Mori, Niklas K. Edvall, Stephanie Rouse, Kjeld Møllgård, Jeffrey R. Holt, Maiken Nedergaard, Barbara Canlon

Science Translational Medicine, vol. 15, 2023, pp. eabq3916

Mapping of CSF transport using high spatiotemporal resolution dynamic contrast-enhanced MRI in mice: Effect of anesthesia

Evan Hunter Stanton, Niklas Daniel Åke Persson, Ryszard Stefan Gomolka, Tuomas Lilius, Björn Sigurðsson, Hedok Lee, Anna Lenice Ribeiro Xavier, Helene Benveniste, Maiken Nedergaard, Yuki Mori

Magnetic Resonance in Medicine, vol. 85, Wiley, 2021, pp. 3326--3342